Why You Have Digestive Problems After Gallbladder Surgery (2024)

Many people don't have issues following gallbladder surgery (cholecystectomy). However, problems after gallbladder removal may occur years later or could occur immediately after the procedure. Symptoms of problems include nausea, abdominal pain after eating, and diarrhea.

Symptoms after gallbladder removal are collectively known as postcholecystectomy syndrome. They are caused by the changes in how bile once stored in the gallbladder now moves through the body.

This article explains why digestive symptoms happen after gallbladder surgery, how your condition can be treated, and which foods to avoid when you no longer have a gallbladder.

Life AfterGallbladder Removal

It is safe to live without a gallbladder, which is one of the reasons gallbladder removal is typically the recommended treatment for gallbladder problems. Your gallbladder's main job is to store bile (a substance needed for digestingfats) and to secrete bile into your small intestine in response to ingesting foods containing fat.

Without your gallbladder, your liver continues to produce bile, but instead of it being sent to the gallbladder for storage, the bile passes into your common bile duct and then makes its way into your small intestine.

Complications of Gallbladder Removal

Most of the time, the body adapts to the loss of the gallbladder. However, there are a few possible digestive complications that people may experience following gallbladder removal.

Postcholecystectomy Diarrhea

Approximately 25% of people who have had their gallbladders removed will experience recurrent problems with diarrhea, a condition known as postcholecystectomy diarrhea.

This problem results from the fact that without the gallbladder, there is nothing to regulate the amount of bile that passes into the small intestine. The resultinghigher amount of bile can create stools that are watery and more frequent. Luckily, for most of these individuals, this problem will resolve itself slowly over time.

Sphincter of Oddi Dysfunction

If you are experiencing ongoing upper abdominal pain following gallbladder removal, you may want to speak with your healthcare provider about a possible problem with your sphincter of Oddi (SO).

The sphincter of Oddi is a valve found within the small intestine that regulates the flow of bile and pancreatic juices. A very small number of people may experience sphincter of Oddi dysfunction (SOD),a functional gastrointestinal disorder (FGD).

In SOD, the sphincter does not relax as it should, preventing the bile and pancreatic juices from entering the small intestine.

Pain from SOD generally occurs a short time after eating. Some people report nausea and vomiting. The pain symptoms of SODare thought to be the result of the excess accumulation of the juices in the ducts.

SODis most often seen in people after gallbladder removal, or in those whohave pancreatitis. It's hard to gauge SOD's actual prevalence after gallbladder removal, as studies report prevalence rates ranging from just 3% up to 40%. SODcan be treated with medication or a procedure known as endoscopic retrograde cholangiopancreatography (ERCP).

Liver Problems

There appears to be a link between gallbladder removal and liver disorders. A 2021 study of 4,497 people who had gallbladder surgery found that 73.3% had a higher risk of liver cirrhosis and 60% had a higher risk of liver fibrosis.

Liver fibrosis refers to scarring of the liver tissue. Mild to moderate fibrosis usually does not cause symptoms. If it's found early enough, fibrosis can be reversed. However, if left untreated, liver fibrosis can lead to liver cirrhosis and liver cancer.

Liver cirrhosis is a condition that causes the liver to become not only scarred but also permanently damaged. Symptoms may not be present until the damage is advanced. Over time, the liver starts to fail.

Diagnosis and Treatment After Gallbladder Removal

Having your gallbladder removed may make you more likely to develop irritable bowel syndrome (IBS). This is especially true for the form of IBS with diarrhea. This is largely due to excessive bile acids and bile acid malabsorption (BAM), a condition in which there is dysfunction with the way that bile acids are processed within the body.

Bile acid diarrhea (BAD) is a similar complication that can occur after gall bladder removal. It's estimated that around 5% to 12% of cholecystectomy patients develop BAD. These patients usually have chronic watery diarrhea and more frequent bowel movements than before surgery.

Postcholecystectomy BAM, BAD, and IBS can be difficult to diagnose. Work with your healthcare provider to identify and resolve digestive problems.

An accurate diagnosis is necessary so you can get the right treatment plan. The American College of Gastroenterology (ACG) warns that testing for BAM is limited in the United States, and testing is not completely validated.

In some cases, ongoing diarrhea following gallbladder removal may be helped by a class of medications known as bile acid-binding agents, or bile acid sequestrants.

These medications include:

• Questran (cholestyramine)
• WelChol (colesevelam)
• Colestid (colestipol)

The ACG does not currently recommend use of these drugs for diarrhea-predominant irritable bowel syndrome (IBS-D), citing a lack of evidence. Still, the experts at ACG realize that these medications may be helpful in some cases, and may be used at the discretion of your medical provider.

When to See Your Healthcare Provider

If you are experiencing ongoing problems with abdominal pain and/or diarrhea, work with your healthcare provider to get an accurate diagnosis. The range of possibilities for your ongoing problems is fairly varied:

• Common bile duct stones
• Chronic pancreatitis
• Dyspepsia
• IBS
• Pancreatic cancer
• SOD

Remember to always mention your surgery when speaking with a new healthcare provider, even if your gallbladder was removed years ago.

Foods to Avoid After Gallbladder Removal

Without your gallbladder participating in the process of digestion, you may need to change your eating habits. If your gallbladder was only removed very recently, you may want to eat a bland diet until your diarrhea symptoms start to ease.

The gallbladder's job is to help you digest fatty food, so having it removed can make these foods problematic for you. Once you're back on a "regular" diet after surgery, you may want to limit or avoid certain foods:

• Fried foods: French fries, onion rings, mozzarella sticks
• High-fat foods: Fatty meats, cheese, ice cream, butter, gravy, chicken skin, pizza, oils
• Foods that cause gas: Beans, broccoli, milk
• Spicy foods: Curry, hot sauce, hot peppers

Gradually reintroducing possible "problem" foods into your diet can help you to learn what bothers you without creating too much discomfort.

Although there isn't necessarily hard science behind these recommendations, you might find the following tipsto be helpful:

• Eat small meals frequently throughout your day
• Try a probiotic
• Try a digestive enzyme

Remember, although coping with symptoms is no fun, there are a few factors (such as your diet) that are in your control.

Summary

Problems after gallbladder removal can occur years later or show up right away. While many people don't have any problems after gallbladder removal, others do. Complications can include postcholecystectomy diarrhea, sphincter of Oddi dysfunction, and liver problems.

Talk to a healthcare provider if you're experiencing problems following cholecystectomy. If you're having symptoms, whether abdominal pain or diarrhea, even years after gallbladder removal, work with your provider to develop an accurate diagnosis. Treatment will depend on the underlying cause. Modifying your diet may help in some cases.