Survival Rates for Merkel Cell Carcinoma (2024)

On this page

  • What is a 5-year relative survival rate?
  • Where do these numbers come from?
  • 5-year relative survival rates for Merkel cell carcinoma
  • Understanding the numbers

Survival rates can give you an idea of what percentage of people with the same type and stage of cancer are still alive a certain amount of time (usually 5 years) after they were diagnosed. They can’t tell you how long you will live, but they may help give you a better understanding of how likely it is that your treatment will be successful.

Keep in mind that survival rates are estimates and are often based on previous outcomes of large numbers of people who had a specific cancer, but they can’t predict what will happen in any particular person’s case. These statistics can be confusing and may lead you to have more questions. Your doctor is familiar with your situation; askhow these numbers may apply to you.

What is a 5-year relative survival rate?

A relative survival rate compares people with the same type and stage of cancer to people in the overall population. For example, if the 5-year relative survival rate for a specific stage of Merkel cell carcinoma (MCC) is 70%, it means that people who have that cancer are, on average, about 70% as likely as people who don’t have that cancer to live for at least 5 years after being diagnosed.

Where do these numbers come from?

The American Cancer Society relies on information from the Surveillance, Epidemiology, and End Results (SEER) database, maintained by the National Cancer Institute (NCI), to provide survival statistics for different types of cancer.

The SEER database tracks 5-year relative survival rates for Merkel cell carcinoma in the United States, based on how far the cancer has spread. The SEER database, however, does not group cancers by AJCC TNM stages (stage 1, stage 2, stage 3, etc.). Instead, it groups cancers into localized, regional, and distant stages:

  • Localized: There is no sign that the cancer has spread outside of the skin where it started.
  • Regional: The cancer has spread outside the skin where it started to nearby structures or lymph nodes.
  • Distant: The cancer has spread to distant parts of the body, such as the lungs, liver, or distant parts of the skin.

5-year relative survival rates for Merkel cell carcinoma

These numbers are based on people diagnosed with MCC between 2012 and 2018.

SEER stage

5-year relative survival rate

Localized

75%

Regional

61%

Distant

24%

All SEER stages combined

65%

Understanding the numbers

  • These numbers apply only to the stage of the cancer when it is first diagnosed. They do not apply later on if the cancer grows, spreads, or comes back after treatment.
  • These numbers don’t take everything into account. Survival rates are grouped based on how far the cancer has spread. But other factors, such as your age and overall health, where on your body the cancer starts, and how well the cancer responds to treatment, can also affect your outlook.
  • People now being diagnosed with MCC may have a better outlook than these numbers show. Treatments have improved over time, and these numbers are based on people who were diagnosed and treated at least 5 years earlier.
  1. Written by
  2. References

Survival Rates for Merkel Cell Carcinoma (1)

The American Cancer Society medical and editorial content team

Our team is made up of doctors andoncology certified nurses with deep knowledge of cancer care as well as editors and translators with extensive experience in medical writing.

SEER*Explorer: An interactive website for SEER cancer statistics [Internet]. Surveillance Research Program, National Cancer Institute. Accessed at https://seer.cancer.gov/explorer/ on February 23, 2023.

Last Revised: March 1, 2023

American Cancer Society medical information is copyrightedmaterial. For reprint requests, please see our Content Usage Policy.

Survival Rates for Merkel Cell Carcinoma (2024)

FAQs

Survival Rates for Merkel Cell Carcinoma? ›

The five-year survival rate for Merkel cell carcinoma is improving. Patients with localized Merkel cell carcinoma have a 78% survival rate while those whose cancer has spread to the lymph nodes or other nearby structures have a 52% survival rate.

Does anyone survive Merkel cell carcinoma? ›

The five-year survival rate for Merkel cell carcinoma is improving. Patients with localized Merkel cell carcinoma have a 78% survival rate while those whose cancer has spread to the lymph nodes or other nearby structures have a 52% survival rate.

How long did Jimmy Buffett have Merkel cell carcinoma? ›

Asgari, MD, MPH, shares details about one of the most dangerous types of skin cancer. After battling skin cancer for four years before his death, "Margaritaville" singer Jimmy Buffett died on September 1, 2023, at age 76, from Merkel cell carcinoma, according to his website.

How likely will Merkel cell skin cancer spread? ›

Merkel cell carcinoma (MCC) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis.

How treatable is Merkel cell carcinoma? ›

Merkel cell cancer (MCC) that has spread to other parts of the body. If MCC has spread to other parts of the body, treatment can often help control the cancer and ease symptoms, but these cancers are very hard to get rid of completely.

What causes death with Merkel cell carcinoma? ›

Merkel cell carcinoma tends to travel first to nearby lymph nodes. Later it may spread to your brain, bones, liver or lungs, where it can interfere with the functioning of these organs. Cancer that has metastasized is more difficult to treat and can be fatal.

Is Merkel cell carcinoma terminal? ›

MCC is a fatal disease, and patients have a poor chance of survival. Moreover, MCC lacks distinguishing clinical features, and thus by the time the diagnosis is made, the tumour usually have metastasized. MCC mainly affects sun-exposed areas of elderly persons.

How survivable is Merkel cell? ›

When Merkel cell carcinoma is discovered and treated early, and hasn't spread to other parts of the body, about 75% of people live for at least 5 years after diagnosis. The outcomes tend to be worse if the cancer spreads; thus, early detection and treatment are important.

Can Merkel carcinoma come back after 2 years? ›

Recurrence-free survival varies by stage. Stages describe the extent of cancer within the body, especially whether the disease has spread (metastasized) from the primary site to other parts of the body. , as shown below, but about 80% of all MCC recurrences occur in the first two years after diagnosis.

How many people in the US have Merkel cell carcinoma? ›

Merkel cell carcinoma (MCC) is a type of skin cancer, but it's not common. About 3,000 people are diagnosed with MCC in the United States each year.

How to beat Merkel cell carcinoma? ›

Treatment for Early Merkel Cell Carcinoma

Surgery and radiation therapy are the most common treatments for people with early-stage MCC (stage I or II, when the main tumor has not spread to lymph nodes or other parts of the body).

Do you feel ill with Merkel cell carcinoma? ›

This aggressive skin cancer can look like a rapidly growing stye or cyst. Unlike a stye or cyst, Merkel cell carcinoma often feels painless.

How fast does Merkel cell carcinoma metastasize? ›

A lesion of metastatic MCC may appear as a 1-3 cm, flesh-colored to red-purple bump that feels firm, is deeper compared to the primary lesion, and grows rapidly over a period of 2-4 weeks.

What is the best hospital to treat Merkel cell carcinoma? ›

Memorial Sloan Kettering Cancer Center has the largest single-center experience with Merkel cell carcinoma of anywhere in the world.

What is the most common complication of Merkel cell carcinoma? ›

Metastatic cancer is more difficult to treat. Merkel cell carcinoma most commonly spreads to your lymphatic system (lymph nodes) first. From there, it may spread to other parts of your body like your bones, lungs, brain or other organs.

Where is the most common site of Merkel cell carcinoma? ›

It most frequently presents on the head and neck region of elderly, white males. Specific risk factors include ultraviolet (UV) exposure, advancing age, and immunosuppression, and its development is associated with Merkel cell polyomavirus (MCPyV) infection.

Does Merkel cell carcinoma always come back? ›

After treatment, many patients are concerned about a potential Merkel cell carcinoma recurrence. The cancer can come back at any point after a patient's initial treatment has been completed – or it might not come back at all.

What is the life expectancy of a MCC? ›

Generally speaking, the life expectancy of a MCC is about 20 years - however, there have been worst-case scenarios where components have failed in under two years.

What is the average age for Merkel cell carcinoma? ›

Age is a risk factor for most types of cancer, including MCC. The average age of diagnosis of MCC is around 70 years old.

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