Bile reflux-Bile reflux - Diagnosis & treatment - Mayo Clinic (2024)

Diagnosis

A description of your symptoms and knowledge of your medical history is usually enough for your doctor to diagnose a reflux problem. But distinguishing between acid reflux and bile reflux is difficult and requires further testing.

You're also likely to have tests to check for damage to your esophagus and stomach, as well as for precancerous changes.

Tests may include:

  • Endoscopy. A thin, flexible tube with a camera (endoscope) is passed down your throat. The endoscope can show bile, peptic ulcers or inflammation in your stomach and esophagus. Your doctor may also take tissue samples to test for Barrett's esophagus or esophageal cancer.
  • Ambulatory acid tests. These tests use an acid-measuring probe to identify when, and for how long, acid refluxes into your esophagus. Ambulatory acid tests can help your doctor rule out acid reflux but not bile reflux.

    In one test, a thin, flexible tube (catheter) with a probe at the end is threaded through your nose into your esophagus. The probe measures the acid in your esophagus over a period of 24 hours.

    In another test called the Bravo test, the probe is attached to the lower portion of your esophagus during endoscopy and the catheter is removed.

  • Esophageal impedance. This test measures whether gas or liquids reflux into the esophagus. It's helpful for people who regurgitate substances that aren't acidic (such as bile) and can't be detected by an acid probe. As in a standard probe test, esophageal impedance uses a probe that's placed into the esophagus with a catheter.

More Information

  • Upper endoscopy

Treatment

Lifestyle adjustments and medications can be very effective for acid reflux into the esophagus, but bile reflux is harder to treat. There is little evidence assessing the effectiveness of bile reflux treatments, in part because of the difficulty of establishing bile reflux as the cause of symptoms.

Medications

  • Ursodeoxycholic acid. This medication may lessen the frequency and severity of your symptoms.
  • Sucralfate. This medication can form a protective coating that protects the lining of the stomach and esophagus against bile reflux.
  • Bile acid sequestrants. Doctors often prescribe bile acid sequestrants, which disrupt the circulation of bile, but studies show that these drugs are less effective than other treatments. Side effects, such as bloating, may be severe.

Surgical treatments

Doctors may recommend surgery if medications fail to reduce severe symptoms or there are precancerous changes in your stomach or esophagus.

Some types of surgery can be more successful than others, so be sure to discuss the pros and cons carefully with your doctor.

The options include:

  • Diversion surgery. During this type of surgery, a doctor creates a new connection for bile drainage farther down in the small intestine, diverting bile away from the stomach.
  • Anti-reflux surgery. The part of the stomach closest to the esophagus is wrapped and then sewn around the lower esophageal sphincter. This procedure strengthens the valve and can reduce acid reflux. However, there's little evidence about the surgery's effectiveness for bile reflux.

Self care

Unlike acid reflux, bile reflux seems unrelated to lifestyle factors. But because many people experience both acid reflux and bile reflux, your symptoms may be eased by lifestyle changes:

  • Stop smoking. Smoking increases the production of stomach acid and dries up saliva, which helps protect the esophagus.
  • Eat smaller meals. Eating smaller, more-frequent meals reduces pressure on the lower esophageal sphincter, helping to prevent the valve from opening at the wrong time.
  • Stay upright after eating. After a meal, waiting two to three hours before lying down allows time for your stomach to empty.
  • Limit fatty foods. High-fat meals relax the lower esophageal sphincter and slow the rate at which food leaves your stomach.
  • Avoid problem foods and beverages. Some foods increase the production of stomach acid and may relax the lower esophageal sphincter. Foods to avoid include caffeinated and carbonated drinks, chocolate, citrus foods and juices, vinegar-based dressings, onions, tomato-based foods, spicy foods, and mint.
  • Limit or avoid alcohol. Drinking alcohol relaxes the lower esophageal sphincter and irritates the esophagus.
  • Lose excess weight. Heartburn and acid reflux are more likely to occur when excess weight puts added pressure on your stomach.
  • Raise your bed. Sleeping with your upper body raised 4 to 6 inches (10 to 15 centimeters) may help prevent reflux symptoms. Raising the head of your bed with blocks or sleeping on a foam wedge is more effective than is using extra pillows.
  • Relax. When you're under stress, digestion slows, possibly worsening reflux symptoms. Relaxation techniques, such as deep breathing, meditation or yoga, may help.

Alternative medicine

Many people with frequent stomach problems, including heartburn, use over-the-counter or alternative therapies for symptom relief. Remember that even natural remedies can have risks and side effects, including potentially serious interactions with prescription medications. Always do careful research and talk with your doctor before trying an alternative therapy.

Preparing for your appointment

Make an appointment with your doctor if you have signs or symptoms common to bile reflux. After your doctor's initial evaluation, you may be referred to a specialist in digestive disorders (gastroenterologist).

Here's some information to help you prepare for your appointment and what to expect from your doctor.

What you can do

  • Write down any symptoms you've been experiencing and for how long.
  • Make a list of your key medical information, including any other conditions for which you're being treated and the names of any medications, vitamins or supplements you're taking.
  • Find a family member or friend who can come with you to the appointment, if possible. Someone who accompanies you can help remember what the doctor says.
  • Write down questions to ask your doctor. Creating your list of questions in advance can help you make the most of your time with your doctor.

Don't hesitate to ask questions during your appointment. Some questions to ask your doctor include:

  • Do I have bile reflux?
  • What treatment approach do you recommend?
  • Are there any side effects associated with these treatments?
  • Are there any lifestyle or dietary changes I can make to help reduce or manage my symptoms?
  • I have other health conditions. How can I best manage them together?

What to expect from your doctor

Your doctor is likely to ask you a number of questions. Being ready to answer them may give you time to go over points you want to spend more time on. You may be asked:

  • What are your symptoms?
  • How long have you had these symptoms?
  • Do your symptoms come and go or stay about the same?
  • If your symptoms include pain, where is your pain located?
  • Have your signs and symptoms included vomiting?
  • Does anything seem to trigger your symptoms, including certain foods or beverages?
  • Have you lost weight without trying?
  • Have you seen a doctor for these symptoms before?
  • What treatments have you tried so far? Has anything helped?
  • Have you been diagnosed with any other medical conditions?
  • Have you had stomach surgery or had your gallbladder removed?
  • What medications are you taking, including prescription and over-the-counter medications, vitamins, herbs and supplements?
  • What is your typical daily diet?
  • Do you drink alcohol? How much?
  • Do you smoke?
Bile reflux-Bile reflux - Diagnosis & treatment - Mayo Clinic (2024)

FAQs

What is the best thing to take for bile reflux? ›

Treatment
  • Ursodeoxycholic acid. This medication may lessen the frequency and severity of your symptoms.
  • Sucralfate. This medication can form a protective coating that protects the lining of the stomach and esophagus against bile reflux.
  • Bile acid sequestrants.

What is the medical treatment for bile reflux? ›

Management and Treatment

Medications to treat bile reflux include: Ursodeoxycholic acid (UDCA), which changes the content of bile in your stomach. Bile acid sequestrants, which bind and disrupt the circulation of bile. Sucralfate, which coats and protects the lining of your stomach and esophagus.

How to tell the difference between bile reflux and acid reflux? ›

Bile Reflux vs, Acid Reflux

Acid reflux is a condition that causes stomach acid to flow back up into the esophagus. Bile reflux is a different condition because it occurs when bile flows into the stomach or esophagus. However, both conditions can be present in the same person.

What are the signs and symptoms of bile reflux? ›

Symptoms
  • Upper abdominal pain that may be severe.
  • Frequent heartburn — a burning sensation in your chest that sometimes spreads to your throat, along with a sour taste in your mouth.
  • Nausea.
  • Vomiting a greenish-yellow fluid (bile)
  • Occasionally, a cough or hoarseness.
  • Unintended weight loss.

Does drinking water help bile reflux? ›

Staying adequately hydrated can ensure the proper passing of food through the gastrointestinal system, reducing the frequency of post-meal acid reflux. Regularly taking small sips of water throughout the day may also help clear acid in the esophagus and treat a GERD-related chronic cough.

What to drink to reduce bile? ›

Some teas that do not relax the sphincter that cause reflux include chamomile tea, licorice tea, and slippery elm tea. These teas can help ease bile reflux symptoms. Avoid peppermint tea as it can aggravate bile reflux by relaxing the lower esophageal sphincter.

Does omeprazole stop bile reflux? ›

Proton pump inhibitors significantly decrease the duration of bile reflux in GERD patients but do not predictably reduce bile reflux to within the normal range.

How do you bring bile acid down? ›

Taking a prescription medicine called ursodiol (Actigall, Urso, Urso Forte). This medicine helps to lower the level of bile acids in your blood. Other medicines to relieve itching also may be an option. Soaking itchy areas in cool or lukewarm water.

How to improve bile naturally? ›

2. EAT FOODS TO IMPROVE BILE FLOW
  1. Organic acids from apple cider vinegar, lemons, and limes.
  2. Bitter herbs such as parsley, cilantro, dandelion, and milk thistle.
  3. Warming spices like ginger, turmeric, and cinnamon.
  4. Prebiotic foods like artichokes, radishes, asparagus, and garlic.
  5. Beets, chicory, and rocket.
Mar 7, 2023

Can you have bile reflux without a gallbladder? ›

In the absence of a gallbladder, disequilibrium in the rate of bile released into the duodenum may lead to duodenogastric bile reflux, resulting in gastric cellular membrane degeneration and, thus, bile reflux gastritis (BRG) (1).

What are the symptoms of too much bile? ›

Excess bile acids entering the colon can cause the classic signs and symptoms of bile acid malabsorption (BAM), including watery stool, urgency and fecal incontinence. Although BAM has been associated with diarrhea for nearly 50 years, it remains an underrecognized and underdiagnosed cause of chronic diarrhea.

What are the lifestyle changes for bile reflux? ›

Making the following changes can help prevent bile from flowing back into the esophagus: losing excess weight. avoiding lying down for 3 hours after eating. limiting high fat foods.

Can a blocked bile duct cause bile reflux? ›

Blockage of duodenal papilla or ampulla of Vater is common characteristics of AP. Once the blockage appears, the occurrence of pancreatic duct obstruction and bile reflux is inevitable.

When should I go to the ER for bile reflux? ›

If people have any of the following symptoms, they should go to the emergency room (ER) or call 911: pressure or squeezing sensation, uncomfortable fullness, or pain in the chest, which may last for a few minutes or come and go. discomfort or pain in the jaw, arms, back, neck, or stomach. shortness of breath.

What are the symptoms of a bile leak? ›

Symptoms of bile leaks vary based on severity and anatomical location. Common symptoms include abdominal pain, nausea, vomiting, fever, chills, jaundice, and abdominal distension.

What can I take for bile acid? ›

A low-fat diet helps to reduce the symptoms of bile acid diarrhoea. Medicines that bind to bile acids in the gut (bowel) are usually very effective. Examples of bile acid binder medicines are colestyramine, colestipol or colesevelam. Colestyramine is the medicine most often used and is usually very effective.

What vitamins are good for bile reflux? ›

The vitamins that may help acid reflux are:
  • Vitamin B9/Folate acid.
  • Vitamin B2/Riboflavin.
  • Vitamin B6.
  • Vitamin A.
  • Vitamin C.
  • Vitamin E.

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